Isolation, Characterization and Purification of Bio-Active Compounds from Andrographispaniculata and Cinnamon verum for Anti-Hiv Activity.

Abstract

Extracts of two ethnobotanically selected medicinal plants used in the Isolation and characterization of bioactive compounds which are investigated against anti-HIV properties. Enzymes and proteins that play a role in the HIV life cycle in which antiviral activity was studied through the pepsin-based assay targeting the HIV promoter activation induced by either the HIV-1 Tat protein. Assay methods to determine antiviral activity include multiple-arm trials, randomized crossover studies. These plants are used to investigate the bioactive compounds like tannins, saponins, flavanoids, coumarins, alkaloids, terpenoids and phenolic compounds against anti-HIV activity.