Please use this identifier to cite or link to this item:
http://13.232.72.61:8080/jspui/handle/123456789/6325
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | A, Shravani | - |
dc.contributor.author | Kumar, A Cendil | - |
dc.date.accessioned | 2023-01-27T11:09:00Z | - |
dc.date.available | 2023-01-27T11:09:00Z | - |
dc.date.issued | 2009-05 | - |
dc.identifier.citation | http://lrc.acharyainstitutes.in:8080/jspui/handle/123456789/6242 | en_US |
dc.identifier.uri | http://13.232.72.61:8080/jspui/handle/123456789/6325 | - |
dc.description | Dissertation | en_US |
dc.description.abstract | Indane-1,3-dione derivatives have shown diverse chemical reactivity and broad spectrum of biological activity. They are reported to possess important therapeutic properties such as antibacterial, antifungal, antiviral, anti-inflammatory, analgesic, anticancer and anti-coagulant activities. 2-Acetylindane-1,3-dione was synthesized from phthalic anhydride and acetyl acetone, which upon reaction with various aldehydes afforded chalcones. The newly synthesized compounds were characterized by physical constants and by spectral methods viz. FT-IR, 1H NMR & Mass spectra. The invivo anti-inflammatory activity and the analgesic activity of the compounds were evaluated by Carrageenan-induced paw edema model in rats by measuring the paw volume and Acetic-acid induced writhing in mice by measuring the number of writhings respectively. Some of the newly synthesized compounds showed good anti-inflammatory and analgesic activity. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Acharya & BM Reddy College of Pharmacy (ABMRCP) | en_US |
dc.subject | 2-Acetylindane-1,3-dione; invivo anti-inflammatory activity; analgesic activity. | en_US |
dc.title | Synthesis, Analgesic And Anti- Inflammatory Activities of Indane-1,3-Dione Derivatives | en_US |
dc.type | Thesis | en_US |
Appears in Collections: | Dissertations |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Shravani abstract.pdf | 61.31 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.